منابع مشابه
40 Anti DNA antibodies UK_-
Double-stranded anti-DNA antibodies are excellent diagnostic markers and follow-up markers for systemic lupus erythematosus (SLE). Less specific than anti-Sm antibodies, anti-PCNA antibodies or anti-ribosomal P antibodies, they are nevertheless much more common. Their sensitivity and specificity for SLE gives them diagnostic value as they are part of the criteria used by the American Rheumatism...
متن کاملDNA receptor dysfunction in systemic lupus erythematosus and kindred disorders. Induction by anti-DNA antibodies, antihistone antibodies, and antireceptor antibodies
The ability of sera from patients with SLE and similar connective tissue diseases to induce dysfunction of the receptor for DNA was studied. All SLE and MCTD sera studied resulted in marked inhibition of DNA receptor binding. Furthermore, the sera from a subgroup of patients with other rheumatic diseases and a surprisingly high percentage of asymptomatic relatives of SLE patients exhibited a si...
متن کاملPrevalence of Toxoplasma gondii Antibodies and DNA in Iranian HIV Patients
Background & Objective: Toxoplasma gondii infection has public health importance and can lead to serious diseases in immunosuppressed patients, such as HIV cases. Appropriate control of T. gondii infection in HIV patients requires information about the prevalence of T. gondii antibodies and DNA in different population. In this study, we aimed to determine the prevalence of Toxo...
متن کاملCell Death and Anti-DNA Antibodies
Autoantibodies are characteristic features of autoimmune diseases (Table 1). In organ or tissue-specific autoimmune diseases, autoantibodies against cell-surface molecules are usually observed. These antibodies (Abs) stimulate or damage the target cells and cause organor tissue-specific diseases. In systemic autoimmune diseases, in addition to anti-cellsurface molecule Abs, Abs against intracel...
متن کاملAnti-dna Antibodies in Hyperimmunized Rabbits
Complement-fixing anti-DNA antibodies were detected in a minority of sera of rabbits hyperimmunized with killed Gram-negative bacteria. The C'-fixing property of DNA was lost after DNase treatment. Preferential reactivity with denatured DNA was observed. The antisera reacted with DNA preparations derived from rabbit bone marrow and thymus, calf thymus, pneumococci, salmon sperm, and Escherichia...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1963
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780060427